Biopharm Closing Bell: 6.30.08

Gainers (% price change)
Last Trade
Change
Mkt Cap

Theragenics Corporation
TGX
3.71
+0.48 (14.86%)
123.93M

XTL Biopharmaceuticals
XTLB
3.84
+0.41 (11.95%)
112.38M

Bio-Imaging Tech, Inc.
BITI
7.40
+0.66 (9.79%)
105.47M

Home Diagnostics, Inc.
HDIX
9.06
+0.68 (8.11%)
161.78M

Sucampo Pharmaceuticals,
SCMP
10.73
+0.80 (8.06%)
447.80M

Losers (% price change)
 

Tongjitang Chinese
TCM
4.17
-2.48 (-37.29%)
139.37M

Cantel Medical Corp.
CMN
10.12
-1.64 (-13.95%)
166.16M

Javelin Pharmaceuticals
JAV
2.32
-0.37 (-13.75%)
113.91M

Molecular Insight
MIPI
5.51
-0.68 (-10.99%)
137.59M

Emeritus Corporation
ESC
14.62
-1.73 (-10.58%)
571.02M

Most Actives (dollar volume)
 

Johnson & Johnson
JNJ
64.34
+0.77 (1.21%)
181.32B

Merck & Co., Inc.
MRK
37.81
+0.83 (2.24%)
81.16B

Pfizer Inc.
PFE
17.47
+0.19 (1.10%)
118.19B

Wyeth
WYE
47.96
+1.87 (4.06%)
63.95B

Myriad Genetics, Inc.
MYGN
45.52
-2.41 (-5.03%)
2.03B

Share and Enjoy:

Myriad Cancels Flurizan Development

One month after licensing EU rights to Lundbeck for $100M upfront (a deal I crapped on by the way), Myriad has discontinued the development of Flurizan for treating Alzheimer’s disease. Surprised? Not me.
As I’ve noted before (in multiple places), I’m not a fan of gamma-secretase modulators for AD. Every trial run so far [...]

Biopharm Closing Bell: 6.24.08

Gainers (% price change)
Last Trade
Change
Mkt Cap

Jazz Pharmaceuticals,
JAZZ
7.60
+0.86 (12.76%)
187.13M

Protherics PLC (ADR)
PTIL
7.24
+0.79 (12.25%)
245.60M

Cytori Therapeutics Inc.
CYTX
6.78
+0.68 (11.15%)
176.98M

DepoMed, Inc.
DEPO
3.45
+0.27 (8.49%)
165.69M

Optimer Pharmaceuticals,
OPTR
8.80
+0.65 (7.98%)
245.74M

Losers (% price change)
 

Cytokinetics, Inc.
CYTK
3.62
-0.34 (-8.59%)
178.47M

NxStage Medical, Inc.
NXTM
4.14
-0.34 (-7.59%)
152.33M

ChemGenex Pharmaceuticals
CXSP
23.80
-1.95 (-7.57%)
294.88M

BMP Sunstone Corp.
BJGP
5.80
-0.42 (-6.75%)
229.05M

Metabolix, Inc.
MBLX
10.67
-0.75 (-6.57%)
242.50M

Most Actives (dollar volume)
 

Merck & Co., Inc.
MRK
37.03
+1.20 (3.35%)
79.49B

Pfizer Inc.
PFE
17.69
+0.31 (1.78%)
119.68B

Johnson & Johnson
JNJ
64.72
+0.43 (0.67%)
182.39B

Wyeth
WYE
47.13
-0.72 (-1.50%)
62.84B

Medtronic, Inc.
MDT
51.59
+0.39 (0.76%)
57.94B

Share and Enjoy:

Immune Design Nets $18M in Series A

 
Image via Wikipedia

Immune Design is the latest company to try and ride the adaptive immune response wave.  Their approach is to create vaccines that: “use novel adjuvants and target dendritic cells.”  Well, that’s instructive.  The fledgling company has three employees and has just raised a hefty $18M in series A funding from Alta Partners, The Column Group [...]

Biopharm Closing Bell: 6.23.08

Gainers (% price change)
Last Trade
Change
Mkt Cap

Barrier Therapeutics,
BTRX
4.03
+2.27 (128.98%)
141.73M

ChemGenex Pharmaceuticals
CXSP
25.75
+7.25 (39.19%)
319.04M

Aspect Medical Systems,
ASPM
6.74
+0.60 (9.77%)
115.98M

MannKind Corporation
MNKD
3.08
+0.19 (6.57%)
312.39M

ImmunoGen, Inc.
IMGN
3.20
+0.19 (6.31%)
137.31M

Losers (% price change)
 

Vanda Pharmaceuticals
VNDA
5.00
-1.30 (-20.63%)
133.26M

BioMarin Pharmaceutical
BMRN
29.12
-3.85 (-11.68%)
2.87B

Jazz Pharmaceuticals,
JAZZ
6.74
-0.86 (-11.32%)
165.96M

Dyax Corp.
DYAX
3.35
-0.41 (-10.90%)
202.91M

Marshall Edwards, Inc.
MSHL
2.10
-0.25 (-10.64%)
144.60M

Most Actives (dollar volume)
 

Pfizer Inc.
PFE
17.38
+0.05 (0.29%)
117.58B

Merck & Co., Inc.
MRK
35.83
+0.70 (1.99%)
76.91B

Wyeth
WYE
47.85
+0.00 (0.00%)
63.80B

Johnson & Johnson
JNJ
64.29
+0.23 (0.36%)
181.18B

Amgen, Inc.
AMGN
45.89
+0.72 (1.59%)
49.96B

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ThromboGenics and BioInvent Ink Deal With Roche

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BioInvent and ThromboGenics have entered into a license agreement with Roche for, TB-403, their novel mAb targeting Placental Growth Factor (PIGF) for the treatment of cancer. Under the terms of the agreement:
Roche will pay BioInvent and ThromboGenics an upfront payment of €50 million. In addition, BioInvent and ThromboGenics could potentially receive up to [...]

Sanofi Gets Into Generics Game

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Sanofi-Aventis plans to make a $2.57 billion (10% premium) offer for Czech generic drugmaker Zentiva, trumping a bid from financial group PPF. Sanofi’s move on Zentiva follows Daiichi Sankyo’s $4.6B offer for India’s top generic company, Ranbaxy.
Generic drug production has traditionally been shunned by large pharmaceutical companies but is now receiving increased interest [...]

Bapineuzumab Fails Trial

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For a drug expected to top $7B in annual sales, even a partial success looks like a failure to me.  I’ve talked about the efficacy in modulating APP for the treatment of Alzheimer’s a few times and Derek Lowe @ has some great articles, so if you’re not familiar, I‘d check them out [...]

Pfizer Waging Battle Over Ranbaxy??

 
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I was on a plane all day, headed to the BIO-LES seminar and didn’t get a chance to read the wire, so there is really no need to throw in my two cents at this point but the WSJ reported that Pfizer may be interested in topping the Daichii bid for Ranbaxy.  
Though [...]

Biopharm Closing Bell: 6.13.08

Top Movers

Generated 4 hours ago

Gainers (% price change)
Last Trade
Change
Mkt Cap

Sequenom, Inc.
SQNM
14.94
+2.10 (16.36%)
678.38M

Chindex Intl, Inc.
CHDX
16.32
+1.72 (11.78%)
203.22M

Helicos BioSciences Corp.
HLCS
4.96
+0.52 (11.71%)
103.84M

DexCom, Inc.
DXCM
8.00
+0.77 (10.65%)
235.80M

Bio-Imaging Tech, Inc.
BITI
7.25
+0.66 (10.02%)
103.33M

Losers (% price change)
 

Maxygen, Inc.
MAXY
3.49
-1.36 (-28.04%)
129.29M

MiddleBrook
MBRK
3.29
-0.31 (-8.61%)
184.26M

Cytori Therapeutics Inc.
CYTX
7.62
-0.57 (-6.96%)
198.91M

Javelin Pharmaceuticals
JAV
2.80
-0.19 (-6.35%)
137.47M

Cardica, Inc.
CRDC
9.26
-0.59 (-5.99%)
145.43M

Most Actives (dollar volume)
 

Pfizer Inc.
PFE
17.99
+0.26 (1.47%)
121.71B

Merck & Co., Inc.
MRK
35.53
+0.13 (0.37%)
76.27B

Johnson & Johnson
JNJ
66.27
+0.58 (0.88%)
186.76B

Bristol Myers Squibb Co.
BMY
20.12
+0.45 (2.29%)
39.83B

Gilead Sciences, Inc.
GILD
54.14
+1.41 (2.67%)
49.94B

Share and Enjoy:

Biopharm Closing Bell: 6.12.08

Top Movers

Generated 5 hours ago

Gainers (% price change)
Last Trade
Change
Mkt Cap

China Medical Tech, Inc.
CMED
39.37
+5.93 (17.73%)
1.08B

Enzo Biochem, Inc.
ENZ
11.26
+1.03 (10.07%)
414.48M

GPC Biotech AG (ADR)
GPCB
4.21
+0.34 (8.71%)
154.97M

Tenet Healthcare Corp.
THC
5.75
+0.45 (8.49%)
2.75B

STAAR Surgical Company
STAA
3.58
+0.27 (8.16%)
105.57M

Losers (% price change)
 

Chindex Intl, Inc.
CHDX
14.53
-6.24 (-30.04%)
180.93M

Jazz Pharmaceuticals,
JAZZ
5.97
-0.78 (-11.56%)
147.00M

Invitrogen Corporation
IVGN
38.53
-4.82 (-11.12%)
3.45B

Electro-Optical Sciences,
MELA
7.75
-0.86 (-9.99%)
119.37M

Cardium Therapeutics Inc.
CXM
2.30
-0.16 (-6.50%)
100.34M

Most Actives (dollar volume)
 

Pfizer Inc.
PFE
17.67
+0.12 (0.68%)
119.54B

Merck & Co., Inc.
MRK
35.29
-0.44 (-1.23%)
75.75B

Johnson & Johnson
JNJ
65.57
+0.37 (0.57%)
184.79B

Invitrogen Corporation
IVGN
38.53
-4.82 (-11.12%)
3.45B

Wyeth
WYE
42.53
-0.41 (-0.95%)
56.71B

Share and Enjoy:

Jazz Pharmaceuticals in Trouble… Still

 
Image via Wikipedia

I always felt a company marketing a date rape drug (GHB) and an antidote for antifreeze (ethylene glycol) poisoning was in for a world of hurt. 
The stock is down 62.5% ($6.75 from $18) from the IPO almost a year ago and today the company filed an S3 with the SEC allowing the sale of [...]

Biopharm Closing Bell: 6.11.08

Gainers (% price change)
Last Trade
Change
Mkt Cap

BioCryst Pharmaceuticals,
BCRX
2.82
+0.19 (7.22%)
107.40M

Angiotech
ANPI
2.76
+0.18 (6.98%)
234.94M

LCA-Vision Inc.
LCAV
8.11
+0.46 (6.01%)
150.23M

Hanger Orthopedic Group,
HGR
14.99
+0.82 (5.79%)
344.10M

Prestige Brands Hldgs,
PBH
11.89
+0.65 (5.78%)
594.51M

Losers (% price change)
 

ImmunoGen, Inc.
IMGN
3.30
-0.38 (-10.33%)
141.60M

Protherics PLC (ADR)
PTIL
8.00
-0.92 (-10.31%)
271.38M

Cadence Pharmaceuticals,
CADX
6.22
-0.69 (-9.99%)
238.57M

MannKind Corporation
MNKD
2.51
-0.26 (-9.39%)
254.58M

Verenium Corporation
VRNM
2.15
-0.22 (-9.28%)
136.84M

Most Actives (dollar volume)
 

Pfizer Inc.
PFE
17.55
-0.39 (-2.17%)
118.73B

Merck & Co., Inc.
MRK
35.73
-0.66 (-1.81%)
76.70B

Johnson & Johnson
JNJ
65.20
-0.42 (-0.64%)
183.75B

Amgen, Inc.
AMGN
42.95
-0.87 (-1.99%)
46.76B

Wyeth
WYE
42.94
-0.40 (-0.92%)
57.25B

Share and Enjoy:

Genentech and Symphogen Team Up For $330M

Image via Wikipedia

I try not to be biased, but it’s not too often I discuss danish biotech companies on this blog.  Today is different. We are having a full international day here at Pharmababble.  First the Daiichi news and now this release of a collaboration from Symphogen and Genentech.  
The specifics of the alliance are [...]

Daiichi Sankyo Goes Generic with Ranbaxy Purchase

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The generic drug business is growing twice as fast as branded medicines so it is no wonder that J&J, Novartis (with the purchase of Hexal and Eon to form Sandoz) and now Daiichi Sankyo are interested.
Daiichi Sankyo announced today that they will buy a controlling interest (50.1%) in India’s Ranbaxy Laboratories for ~$4.6B, [...]